Course syllabus P15-0099-I - Bioactive metabolites of microorganisms (FBFS - SS 2020/2021)

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University: Slovak University of Agriculture in Nitra
Course unit code: P15-0099-I
Course unit title: Bioactive metabolites of microorganisms
Planned types, learning activities and teaching methods:
1 hour weekly / 13 hours per semester of study (on-site method)
2 hours weekly / 26 hours per semester of study (on-site method)

Applied Biology - master (required), 2. semester
Food Safety and Control - master (required), 2. semester
Agrobiotechnology - master (elective), 2. semester
Food Safety and Control - master (elective), 2. semester
Level of study: 2.
Prerequisites for registration:
Assesment methods :
During the semester there will be 1 written test for 30 points and project for 10 points. Final test will be for 60 points. To obtain an evaluation A is needed to obtained at least 93 points, for the evaluation B at least 86 points, C at least 79 points, D at least 72 points and E at least 64 points.
Learning outcomes of the course unit:
After completion of the subject the student understands the issue of the bioactive metabolites production (antibiotics, enzymes, organic acids, vitamins, mycotoxins, pigments, aromatic substances, antifungal, herbicide, insecticide, pesticide compounds, stimulators of plant growth, etc.) by microorganisms. Student will be able to characterize the microorganisms, which metabolites can be used, in particular, in the food, agricultural, pharmaceutical or cosmetic practice. Student will learn knowledge about their use in biotechnology and the ways to control their metabolism in the laboratory conditions.
Course contents:
Primary and secondary metabolites of microorganisms. Bioactive products of microorganisms. Metabolism of productive microorganisms and influencing factors. Microorganisms utilisable in biotechnology. The regulation of metabolism of microorganisms for the benefit of the bioactive metabolites biosynthesis. Methods of detection and extraction of bioactive substances.
Recommended or required reading:
JAVOREKOVÁ, S. -- KRÁLIKOVÁ, A. -- LABUDA, R. -- LABUDOVÁ, S. -- MAKOVÁ, J. Biológia pôdy v agroekosystémoch. 1st ed. Nitra : Slovenská poľnohospodárska univerzita v Nitre, 2008. 349 p. ISBN 978-80-552-0007-1.
JAVOREKOVÁ, S. -- MEDO, J. Laboratórny manuál k predmetu mikrobiológia. 1st ed. Nitra : Slovenská poľnohospodárska univerzita, 2013. 121 p. ISBN 978-80-552-0985-2.
JAVOREKOVÁ, S. -- MAKOVÁ, J. Mikrobiológia. 1st ed. Nitra : Slovenská poľnohospodárska univerzita, 2012. 135 p. ISBN 978-80-552-0760-5.

Betina, V. 1990. Mykotoxíny. Chémia – biológia – ekológia. ALFA : Bratislava, 1990. 284 s. ISBN 80-05-00631-4.
Kieser, T. – Bibb, M. J. – Buttner, M. J. – Chater, K. F. – Hopwood, D. A. 2000. Practical Streptomyces Genetics. The John Innes Foundation : Norwich, 2000. 613 p. ISBN 0-7084-0623-8.
Ramawat, K. G. – Merillon, J. M. 2007. Biotechnology. Secondary Metabolites. Plants and Microbes. Science Publishers : Enfield, 2007. 565 p. ISBN 978-1-57808-428-9.

Language of instruction: Slovak
Evaluation of course unit:
Assessed students in total: 133

15,0 %15,8 %
22,6 %
16,5 %24,8 %
5,3 %
Name of lecturer(s):
prof. Ing. Soňa Javoreková, PhD. (examiner, instructor, lecturer, person responsible for course)
Ing. Zuzana Mašková, PhD. (examiner, instructor, lecturer)
Last modification:
18. 3. 2020
Supervisor: prof. Ing. Soňa Javoreková, PhD. and programme supervisor

Last modification made by Ing. Martin Mastík, PhD. on 03/18/2020.

Type of output: