The effect of flavonoids on adipogenesis and oxidative stress in culture of human and mice cells

Supervisor: doc. Ing. Anna Kalafová, PhD.

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Project description:Fat tissue is a metabolic and endocrine organ. The adipocyte size positively correlates with the production of pro-inflammatory adipoxins and cytokines. The major role in the pathophysiology of insulin resistance and dyslipidemia is adiponectin and tumor necrosis factor-alpha. TNF-α is an activator of pro-inflammatory signaling cascades in fat tissue, which causes oxidative stress (OS).
Kind of project:VEGA (Vedecká grantová agentúra MŠVVaŠ SR)
Department:Department of Animal Physiology (FBFS)
Project status:Rejected
Project start date :01. 01. 2016
Project close date:31. 12. 2019
Number of workers in the project:4
Number of official workers in the project:0