The effect of flavonoids on adipogenesis and oxidative stress in culture of human and mice cellsSupervisor: doc. Ing. Anna Kalafová, PhD.
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Fat tissue is a metabolic and endocrine organ. The adipocyte size positively correlates with the production of pro-inflammatory adipoxins and cytokines. The major role in the pathophysiology of insulin resistance and dyslipidemia is adiponectin and tumor necrosis factor-alpha. TNF-α is an activator of pro-inflammatory signaling cascades in fat tissue, which causes oxidative stress (OS).
|Kind of project:||VEGA ()|
|Department of Animal Physiology (FBFS)|
Project start date :
|01. 01. 2016|
Project close date:
31. 12. 2019
Number of workers in the project:
Number of official workers in the project: